8.
Graptophyllum pictum (GP) is used to treat anemiain some traditional communities. To understand this practice, we had prepared GP tea leaves for the management of phenylhydrazine-induced anemia in rats. An experimental protocol was built with six groups of six rats each. Rats in normal group were fed with standard food and water ad libitum. The rest of rats received an intraperitoneal injection of...
F. Kouoh Elombo *, C. E. Yando, R. V. Djuikwo, H. Abdul, R. S. Touole, E. Fokou and P. Moundipa Fewou
Department of Biochemistry, Faculty of Science, University of Yaoundé I, 812 Yaoundé, Cameroon.
DOI: 10.13040/IJPSR.0975-8232.17(6).1762-69
1762-1769
9.
Background: Pain management remains challenging with current analgesics associated with significant adverse effects. Lactium, a milk protein hydrolysate containing α-casozepine with GABA-A receptor affinity, has unexplored analgesic potential. Methods: Twenty-four male Swiss albino mice (20-30g) were randomly divided into four groups (n=6): control (normal saline 10ml/kg), standard (pentazocin...
C. D. Jaypriya *, V. Arun Kumar and B. Sharmila
Department of Pharmacology, Government Medical College, Thiruvallur, Tamil Nadu, India.
DOI: 10.13040/IJPSR.0975-8232.17(6).1770-77
1770-1777
10.
Introduction: Nonalcoholic fatty liver disease (NAFLD) represents a metabolic spectrum ranging from simple steatosis to cirrhosis and hepatocellular carcinoma. Although classically associated with obesity, lean individuals particularly in Asian populations are increasingly affected due to higher visceral adiposity at lower body mass index (BMI). The Asia-Pacific guideline defines lean as BMI <2...
Ashis Kumar Saha *, Koushik Mal and Puja Mahato
Jagannath Gupta Institute of Medical Sciences & Hospital, Budge Budge, Kolkata, West Bengal, India.
DOI: 10.13040/IJPSR.0975-8232.17(6).1778-96
1778-1796
11.
Gastric ulcers (GU) represent a world prevalence of 5-10% and a 10.4% prevalence in Cameroon. The frequent use of non-steroidal anti-inflammatory drugs (NSAIDs) is one of the major causes. The effective treatments available are expensive and have serious side effects. Treating GU with medicinal plants could be a safer alternative solution. In this work, we formulated an anti-ulcer syrup using th...
A. Y. Mely Keabou, F. Kouoh Elombo *, E. Chieugo Ngoune, F. Tatene Dok-koimbi, Kemmegne Sandrine, Frederic Nico Njayou and P. Moundipa Fewo
University of Yaoundé I, Faculty of Sciences -Department of Biochemistry, Laboratory of Pharmacology and Toxicology, 812 Yaoundé, Cameroon.
DOI: 10.13040/IJPSR.0975-8232.17(6).1797-02
1797-1802
12.
Ambrisentan is an endothelin receptor antagonist for rapid administration during early disease progression to provide therapeutic benefit. This study aimed to develop Ambrisentan as a fast-dissolving oral film (FDOF) and evaluate the physicochemical and performance characteristics of the formulated films. The FDOFs were prepared using film-forming polymers, including hydroxypropyl methylcellulose ...
Jisha James *, John Thomas and Vivek
MGM College of Pharmacy, Vilayancode PO Pilathara, Kannur, Kerala, India.
DOI: 10.13040/IJPSR.0975-8232.17(6).1803-14
1803-1814
