1.
Me-too drugs are pharmacologically active compounds that have structural similarities to the first-in-class compound. Approximately 60% of drugs on the World Health Organization's list of essential treatments fall into the "me-too" category. They are an important but contentious component of modern pharmacotherapy, with minor improvements in cost, efficacy, side effects, and compliance on one side...
Anurag Motwani *, Kiran A. Bhave and Tejal Patel
Department of Pharmacology, HBT MC & Dr. R. N. Cooper Hospital Vile Parle West, Mumbai, Maharashtra, India.
DOI: 10.13040/IJPSR.0975-8232.17(2).408-16
408-416
2.
Background: Alveolar bone defects are common in dentistry. Bone tissue repair involves a complex inflammatory process, regulated by osteoprogenitor cells from the periosteum and endosteum, which are vital for new bone matrix formation. Recently, plant extracts have gained attention as potential treatments for bone lesions. Moringa oleifera exhibits various medicinal properties, largely due to its ...
Reetika Gaddale * and Ramesh Chowdhary
Department of Periodontology, Sri Siddhartha Dental College, S. S. A. H. E. University, Tumkur, Karnataka, India.
DOI: 10.13040/IJPSR.0975-8232.17(2).417-26
417-426
3.
Traditional Siddha Medicine (TSM) is one of the oldest forms of traditional medicine, having its roots in South India's ancient Tamil Nadu. One of the Internal Medicines available in Classical text Brammamuni Karukkidai Choothiram is Nilavagai Chooranam. It is used to treat Malakkattu (Constipation), Vaaivu (One of the three humours), Soodukollal (Intense heat in pelvic region), Sori & Sirangu...
S. Venkatesh *, H. Nalini Sofia and H. Vetha Merlin Kumari
Department of Maruthuvam, National Institute of Siddha, Tambaram Sanatorium, Chennai, Tamil Nadu, India.
DOI: 10.13040/IJPSR.0975-8232.17(2).427-36
427-436
4.
This review emphasizes the effectiveness of bioanalytical techniques in pharmacokinetic, pharmacodynamics, and toxicological evaluations, highlighting their essential role in drug development. The quantitative assessment of pharmaceuticals, metabolites, and endogenous chemicals in biological matrices such blood, plasma, urine, and cerebrospinal fluid was the focus of a thorough examination of bioa...
Jayashri Jagtap *, Akanksha Borhade, Manasi Mhetar and Rajashree Chavan
Department of Pharmaceutical Chemistry, PDEA’s Seth Govind Raghunath Sable College of Pharmacy, Saswad, Pune, Maharashtra, India.
DOI: 10.13040/IJPSR.0975-8232.17(2).437-46
437-446
5.
Polymeric nanoparticles (NPs) are tiny particles with a size between 10 and 1000 nm, with the ability to contain or have active substances surface-adsorbed onto the polymeric core. Both nanospheres and nano capsules are under the umbrella of "nanoparticles," which are distinguished by the morphological organization. For the targeted delivery of medications used to treat a variety of disorders, pol...
Randhawan Bhagyashri and Hapse Sandip A. *
Dr. V. V. P. F’s College of Pharmacy, Vilad Ghat, Ahilyanagar, Maharashtra, India.
DOI: 10.13040/IJPSR.0975-8232.17(2).447-58
447-458
